The world has changed dramatically because many people now have psychic abilities that open up previously unimaginable possibilities as a result of a unique hormone. But the prior utopia swiftly turns into a gloomy reality when insane, deformed people - the so-called Others - physically fall from the sky and attempt to consume human brains. Now, in order to prevent humanity's ultimate annihilation, superhuman abilities must be deployed in combat.
The Other Defense Force, which includes Yuito Sumeragi, a boy who was saved as a child by this same organization and who now aspires to become an elite warrior with the aid of his skill for psychokinesis, is essentially the final line of defense against these strong adversaries. Kasane Randall is a gifted young woman who was specifically sought after by the AAS because of his skills. She quickly begins to experience odd, prophetic dreams, and she and Yuito soon find themselves in the middle of saving the world.